Copa Libertadores
Round of 16
Atlético Nacional
LIVE GAME
13 August
01:30
(WAT)
São Paulo

Atlético Nacional vs São Paulo: prediction & betting odds 13 August 2025

The first leg of the 2025 Copa Libertadores Round of 16 between Atletico Nacional (Colombia) and Sao Paulo (Brazil) will take place on August 13 at the Gran Parque Central Stadium in Montevideo. Atletico Nacional vs. Sao Paulo: prediction and betting odds, statistics.

Atletico Nacional

Javier Gandolfi's side qualified for the playoffs by finishing second in Group F. The team won all three home matches but lost all three away games. Notably, the Colombians prefer uncompromising football, as evidenced by their 13 previous Copa Libertadores matches without a draw (5 wins and 8 losses). The last time Atletico reached the tournament's playoffs was in 2023, when they advanced to the quarter-finals.


In the offseason, several free agents joined the club, and a number of players were brought in on loan. Among them are midfielder Mateus Uribe and goalkeeper David Ospina. The club sold forward Oscar Perea and defender Edier Ocampo.


  • At least one team failed to score in regulation time in 8 of Atletico Nacional's last 9 Copa Libertadores matches.
  • Atletico has not lost in regulation time in 19 of their last 22 home matches in this tournament (14 wins and 5 draws).
  • Three or more goals were scored in regulation time in 6 of the team's last 8 home matches in the Copa Libertadores.

Predicted lineup for Atletico Nacional (4-2-3-1)

Arlen Castillo – Joan Castro, Simon Garcia, Andres Salazar, Cesar Haidar – Jorman Campuzano, Elkin Rivero – Marlos Moreno, Juan Baúsa, Billy Arce – Facundo Batista.

Sao Paulo

The Brazilians easily and confidently won Group D, securing 4 wins and 2 draws. Interestingly, only Palmeiras (18 points) performed better in the group stage than Sao Paulo (14 points). Additionally, the team conceded only 4 goals, ranking them among the top defensive teams in the group stage of this year's Copa Libertadores. This marks the sixth consecutive season that the Brazilians have reached the playoffs. Last year, the team advanced to the quarter-finals, where they lost on penalties to the eventual tournament winners, Botafogo.


In June, Hernan Crespo took over as head coach. The team also sold forward William Gomes and defender Diego Costa. Midfielders Santiago Longo and Marcos Antonio, as well as defender Jamal Lewis, were brought in on loan. The club also strengthened its squad for free with defender Wendell and midfielder Oscar.


  • The club has not lost in regulation time in 15 consecutive Copa Libertadores matches (9 wins and 6 draws).
  • No more than 2 goals were scored in regulation time in 10 of Sao Paulo's last 12 matches in this tournament.
  • The team has not conceded in regulation time in their last 5 away matches in the Copa Libertadores.

Predicted lineup for Sao Paulo (3-5-2)

Enrique Rafael – Nahuel Ferraresi, Sabino, Alan Javier Franco – Damian Bobadilla, Mike, Rodriguinho, Marcos Antonio, Enzo Hernan Diaz – Andre Oliveira Silva, Lucas Ferreira.


Midfielders Oscar and Luis Gustavo, defenders Robert Arboleda and Wendell, as well as forwards Ryan Francisco and Jonathan Calleri, are unavailable due to injuries.

Referee

Gustavo Tejera (Uruguay)


Matches – 6 (International matches, 2025);

Yellow cards shown (including second yellows) – 30;

Average yellow cards per match – 5;

Red cards shown – 0;

Average fouls per match – 24;

Penalties – 0%.

Atletico Nacional vs. Sao Paulo: Match Prediction

Bookmakers seem to underestimate the Serie A representative. The Brazilians have been regular participants in the Copa Libertadores in recent years and consistently reach the playoffs. Even away from home, the club remains a threat to any opponent, having not suffered a defeat in regulation time in their last 7 away matches in this tournament – 5 wins and 2 draws.


Moreover, Sao Paulo is very difficult to score against. In their last 7 away matches in the Copa Libertadores, the club has conceded just 1 goal. The Colombians also boast decent home statistics, but in their last 11 matches, they failed to win in regulation time in 6 games (3 draws and 3 losses). Therefore, with caution, I suggest the prediction – Sao Paulo with a handicap (0)


* The starting lineup for each team is based on their previous match.

Atlético Nacional vs São Paulo Odds

1X2
DOUBLE CHANCE
OVER/UNDER
BTTS
HANDICAP

Current season

Logo Atlético Nacional Logo São Paulo
3 Wins 4
3 Lost 0
0 Draws 2
1.17 GF per game 1.67
1 GA per game 0.67
4.83 Corners per game 3.83
2.17 Yellow cards per game 1.83

Copa Libertadores: previous matches in the tournament

Atlético Nacional
28.05.25
Nacional Montevideo
Atlético Nacional
L
14.05.25
Atlético Nacional
Bahia
W
09.05.25
Atlético Nacional
Internacional
W
25.04.25
Bahia
Atlético Nacional
L
10.04.25
Internacional
Atlético Nacional
L
03.04.25
Atlético Nacional
Nacional Montevideo
W
More matches
São Paulo
27.05.25
São Paulo
Talleres de Córdoba
W
15.05.25
São Paulo
Libertad
D
06.05.25
Alianza Lima
São Paulo
W
24.04.25
Libertad
São Paulo
W
11.04.25
São Paulo
Alianza Lima
D
03.04.25
Talleres de Córdoba
São Paulo
W
More matches

Group stage

CONMEBOL Libertadores: Group F
Team
Played
Matches played
W
D
L
Goals
Goals
Points
Points
1
Internacional
  3:0 2:1 3:3 6 3 2 1
12:8
11
2
Atlético Nacional
3:1   1:0 3:0 6 3 0 3
7:6
9
3
Bahia
1:1 1:0   1:3 6 2 1 3
5:7
7
4
Nacional Montevideo
0:2 1:0 0:1   6 2 1 3
7:10
7

Team lineups

Atlético Nacional

Javier Marcelo Gandolfi
coach
Player Matches Goals
Line-up
David Ospina
gk. 5 -6
Andrés Román
df. 6 0
Camilo Damián Cándido Aquino
df. 6 0
Teofilo Gutierrez
df. 6 0
Juan José Arias Henao
mf. 6 0
Edwin Cardona
mf. 5 0
Juan Manuel Zapata Zumaque
mf. 3 0
Jorman David Campuzano Puentes
mf. 0 0
Alfredo José Morelos Aviléz
fw. 6 1
Marino Hinestroza
fw. 5 1
Marlos Moreno Durán
fw. 0 0
Substitutes
Harlen Alfred Castillo Moreno
gk. 1 0
Joan Sebastián Castro Dinas
df. 1 0
Andrés Salazar Osorio
df. 0 0
César Rafael Haydar Villarreal
df. 0 0
Billy Arce
mf. 5 1
Mateus Uribe
mf. 3 0
Simón García Valero
mf. 1 0
Elkin José Rivero Almario
mf. 0 0
Juan Francisco Bauza
mf. 0 0
Luis Miguel Landázuri
mf. 0 0
Juan Manuel Rengifo Duque
fw. 0 0
São Paulo

Hernán Jorge Crespo
coach
Player Matches Goals
Line-up
Henrique Roberto Rafael
gk. 6 -4
Enzo Hernán Díaz
df. 6 0
Nahuel Ferraresi
df. 6 0
Alan Javier Franco
df. 5 0
Cédric Ricardo Alves Soares
df. 5 0
José Sabino Chagas Monteiro
df. 2 1
Alisson Euler de Freitas Castro
mf. 5 1
Damián Josué Bobadilla Benítez
mf. 4 0
Marcos Antônio
mf. 4 0
Luciano
fw. 6 1
André Oliveira Silva
fw. 5 3
Substitutes
Young Navarro Moraes
gk. 0 0
Patryck Lanza dos Reis
df. 0 0
Pablo Gonçalves Maia Fortunato
mf. 2 0
Felipe Negrucci Berdague
mf. 0 0
Luan Vinícius da Silva Santos
mf. 0 0
Maik Gomes Viegas
mf. 0 0
Rodriguinho
mf. 0 0
Aldemir dos Santos Ferreira
fw. 5 2
Henrique Fabiano do Carmo
fw. 1 0
Lucas Moura
fw. 1 0
Gonzalo Andrés Tapia Dubournais
fw. 0 0
Juan Ignacio Dinenno de Cara
fw. 0 0
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